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Meta-analysis of the incidence and influencing factors of sleep disorders in patients with coronary heart disease

Published on Feb. 02, 2026Total Views: 21 timesTotal Downloads: 5 timesDownloadMobile

Author: LI Jialu ZHONG Xuelian HE Wei GUO Hongxia

Affiliation: West China Hospital, Sichuan University/ West China School of Nursing, Sichuan University, Chengdu 610041, Sichuan Province, China

Keywords: Coronary heart disease Sleep disorders Influencing factors Systematic review

DOI: 10.12173/j.issn.1004-5511.202502100

Reference: Li JL, Zhong XL, He W, et al. Meta-analysis of the incidence and influencing factors of sleep disorders in patients with coronary heart disease[J]. Yixue Xinzhi Zazhi, 2026, 36(1): 80-87. DOI: 10.12173/j.issn.1004-5511.202502100. [Article in Chinese]

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Abstract

Objective  To analyze the prevalence of sleep disorders among patients with coronary heart disease (CHD) and identify their associated influencing factors, thereby providing evidence to improve sleep quality in this patient population.

Methods  Systematic retrieval of Cochrane Library, PubMed, Web of Science, Embase, China National Knowledge Infrastructure (CNKI), VIP Database, WanFang Database, and Chinese Biomedical Literature Database was conducted to obtain relevant research on the current situation and influencing factors of sleep disorders in patients with CHD, with the retrieval time from the inception of the database to March 2025. Meta-analysis was performed using R Studio 4.3.3 software.

Results  A total of 14 articles were included, with a total sample size of 3,252 cases. The incidence rate of sleep disorders in patients with CHD was 58% [95%CI (46%, 69%)], among which female [OR=1.76, 95%CI (1.55, 2.01)], urban medical insurance coverage [OR=1.83, 95%CI (1.03, 3.27)], elderly [OR=1.21, 95%CI (1.05, 1.41)], anxiety [OR=2.17, 95%CI (1.29, 3.66)], depression [OR=3.23, 95%CI (1.53, 6.80)], and pain [OR=1.83, 95%CI (1.23, 2.73)] were the main risk factors of sleep disorders in patients with CHD. In contrast, good social support [OR=0.86, 95%CI (0.84, 0.89)] serves as a protective factor.

Conclusion  Sleep disorders are highly prevalent among patients with CHD. Being female, having urban health insurance, elderly, anxiety, depression, pain interference, and lack of social support are significant risk factors for sleep disturbances in this population.

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