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HomeArticlesVol 31,2021 No.3Detail

Report of 2 cases of diabetes insipidus and pituitary stalk thickening

Published on May. 18, 2021Total Views: 12926 timesTotal Downloads: 4106 timesDownloadMobile

Author: Yuan WU 1 Chu-Qi GAO 1 Xiao-Qun MA 4 Juan WEN 2 Li CUI 3 Ben-Zhang ZHU 1 Xiao-Yan WU 1 Yi WANG 1

Affiliation: 1. Department of Endocrinology, the first Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, China 2. Department of Internal Medicine, Xunyang County Hospital, Ankang 725700, Shaanxi Province, China 3. Department of Endocrinology, Gansu Jiugang Hospital, Jiayuguan 735100, Gansu Province, China 4. Department of Endocrinology, Wuzhong City People's Hospital, Wuzhong 750000, Ningxia Province, China

Keywords: Diabetes insipidus Pituitary stalk thickening Langerhans’ cell histiocytosis

DOI: 10.12173/j.issn.1004-5511.202010023

Reference: Wu Y, Gao CQ, Ma XQ, Wen J, Cui L, Zhu BZ, Wu XY, Wang Y. Report of 2 cases of diabetes insipidus and pituitary stalk thickening[J]. Yixue Xinzhi Zazhi, 2021, 31(3): 231-236. DOI: 10.12173/j.issn.1004-5511.202010023.[Article in Chinese]

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Abstract

To analyze the clinical data of 2 patients with diabetes insipidus (DI) who had pituitary stalk thickening (PST) and review the literature. The 2 patients were a 16-year-old boy and a 13-year-old girl who presented with complaints of thirst and polyuria. Both pituitary MRIs suggested PST. The boy had central diabetes insipidus (CDI), while the girl had both CDI and anterior pituitary dysfunction (APD). Langerhans’ cell histiocytosis (LCH) and germinoma were diagnosed pathologically by pituitary stalk biopsy. PST is one of the most common clinical imaging manifestation in CDI patients suggesting inflammatory or neoplastic infiltration. The differential diagnosis of PST-related diseases is important in clinical practice with pituitary biopsy being the gold standard for diagnosis.

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