Objective  To systematically evaluate the incidence and influencing factors of medication discrepancies in patients with cardiovascular disease (CVD) in China.

Methods  CNKI, Wanfang, VIP, SinoMed, PubMed, Embase, Web of Science, CINAHL, and the Cochrane Library databases were searched from their inception to December 2024. Literature on the incidence and influencing factors of medication discrepancies in patients with CVD in Chinese was included. Meta-analysis was performed using R 4.3.2 software.

Results  A total of 22 articles were included, involving 6,278 patients. Meta-analysis results showed that the prevalence of medication discrepancies among Chinese CVD patients was 67% [95%CI (56%, 76%)]. High monthly household income, high education level, good family functioning, living with others, fewer combined chronic diseases, a low Charlson comorbidity index, and male sex were protective factors for medication discrepancies, while a high number of medications used and the presence of adverse drug reactions were risk factors.

Conclusion  The prevalence of medication discrepancies among Chinese patients with CVD is high. Clinicians should identify high-risk patients based on these factors and conduct early screening and intervention to prevent medication discrepancies.

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