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Transurethral plasmakinetic resection of prostate in high-risk benign prostatic hyperplasia patients: a multicenter prospective study

Published on Apr. 29, 2024Total Views: 2077 timesTotal Downloads: 1406 timesDownloadMobile

Author: LI Fei 1, 2 GENG Jie 3 CHEN Hongbo 4 ZHOU Zhijun 5 LIU Xiaohua 6 SHI Hongbo 7 DU Dan 8 ZHU Tao 9 ZHANG Jingyu 10 LI Xiaodong 11 QUE Hui 12 SONG Hongfei 13 YAO Qisheng 14 DOU  Zhongling 15 RUAN Jianzhong 16 ZHENG Jiang 17 ZHU Ziqing 18 REN Xuanyi 19 HUANG Qiao 2 GONG Kan 20 LIU Tongzu 1 HE Dalin 21 ZENG Xiantao 1, 2

Affiliation: 1. Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan 430071, China 2. Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, China 3. Department of Urology, Suizhou Central Hospital, Suizhou 441300, Hubei Province, China 4. Department of Urology, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi Tujia and Miao Autonomous Prefecture 445000, Hubei Province, China 5. Department of Urology, The First People’s Hospital of Tianmen in Hubei Province, Tianmen 431700, Hubei Province, China 6. Department of Urology, Minda Hospital of Hubei Minzu University, Enshi Tujia and Miao Autonomous Prefecture 445000, Hubei Province, China 7. Department of Urology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Sciences, Xiangyang 441100, Hubei Province, China 8. Department of Urology, The Second People's Hospital of Yichang, Yichang 443000, Hubei Province, China 9. Department of Urology, The Sixth Hospital of Wuhan, Wuhan 430015, China 10. Department of Urology, The Third Hospital of Wuhan, Wuhan 430060, China 11. Department of Urology, Huaihe Hospital of Henan University, Kaifeng 475000, Henan Province, China 12. Department of Urology, Huanggang Central Hospital, Huanggang 438000, Hubei Province, China 13. Department of Urology, Qianjiang Central Hospital, Qianjiang 433100, Hubei Province, China 14. Department of Urology, Taihe Hospital, Affiliated Hospital of Hubei University of Medicine, Shiyan 442000, Hubei Province, China 15. Department of Urology, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang 471000, Henan Province, China 16. Department of Urology, Xiaogan First People's Hospital, Xiaogan 432000, Hubei Province, China 17. Department of Urology, The First People's Hospital of Jingzhou, Jingzhou 434000, Hubei Province, China 18. Department of Urology, CR&WISCO General Hospital, Wuhan 430080, China 19. Department of Urology, Kaifeng Central Hospital, Kaifeng 475000, Henan Province, China 20. Department of Urology, Peking University First Hospital, Beijing 100034, China 21. Department of Urology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China

Keywords: Transurethral plasmakinetic resection of prostate Benign prostatic hyperplasia High-risk patients Cardiovascular diseases

DOI: 10.12173/j.issn.1004-5511.202402013

Reference: Li F, Geng J, Chen HB, Zhou ZJ, Liu XH, Shi HB, Du D, Zhu T, Zhang JY, Li XD, Que H, Song HF, Yao QS, Dou ZL, Ruan JY, Zheng J, Zhu ZJ, Ren XY, Huang Q, Gong K, Liu TZ, He, DL, Zeng XT. Transurethral plasmakinetic resection of prostate in high-risk benign prostatic hyperplasia patients: a multicenter prospective study[J]. Yixue Xinzhi Zazhi, 2024, 34(4): 381-390. DOI: 10.12173/j.issn.1004-5511.202402013.[Article in Chinese]

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Abstract

Objective  To investigate the clinical efficacy of transurethral plasmakinetic resection of prostate (TUPKP) in treating high-risk benign prostatic hyperplasia (BPH) patients.

Methods  A prospective multicenter study design was employed. Patients with high-risk BPH treated with TUPKP were enrolled in the urology departments of 20 hospitals nationwide according to the inclusion and exclusion criteria. Relevant data regarding patient baseline, perioperative period, and 3-month postoperative follow-up were analyzed to evaluate efficacy and safety.

Results   From September 2016 to December 2018, a total of 229 high-risk BPH patients were enrolled. Compared to baseline at the 3-month follow-up, the change in the International Prostate Symptom Score was -17.28[95%CI(-18.02, -16.54)], the change in maximum urinary flow rate was 5.61[95%CI(0.68, 10.54)]mL·s-1, the change in residual urine volume was -84.50 [95%CI(-96.49, -72.51)] mL, and the change in quality of life score was -3.24[95%CI(-3.42, -3.06)],all showing significant differences(P<0.05). The incidence of intraoperative and postoperative complications was low, and no surgery-related adverse events occurred.

Conclusion  TUPKP can be used to treat high-risk BPH patients, and it is recommended to be performed by skilled surgeons.

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