Sodium valproate is widely used in clinical practice as a broad-spectrum anti-epileptic. The common adverse reactions are nausea, vomiting, skin rash, ataxia and leukopenia. There are few reported cases of refractory hypoproteinemia ascites. We retrospectively analyzed the diagnosis and treatment of a case of refractory hypoalbuminemia ascites caused by sodium valproate in the First Affiliated Hospital of Nanchang University, aiming to provide clinician introduction with the benifit of our experience.

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