Welcome to visit Zhongnan Medical Journal Press Series journal website!

Short-term follow-up study of rotating stable prosthesis and simple hinge prosthesis in the treatment of malignant bone tumors of proximal tibia

Published on Aug. 21, 2020Total Views: 4169 timesTotal Downloads: 2336 timesDownloadMobile

Author: Zi-Meng CHEN Huo-Wen LIU Min-Hao WU Jun LEI Lin CAI *

Affiliation: Department of Spine Surgery and Musculoskeletal Tumor, Zhongnan Hospital of Wuhan University, Wuhan 430071, China

Keywords: Tibia Bone neoplasms Malignancy Prostheses

DOI: 10.12173/j.issn.1004-5511.2020.04.02

Reference: Chen ZM, Liu HW, Wu MH, Lei J, Cai L. Short-term follow-up study of rotating stable prosthesis and simple hinge prosthesis in the treatment of malignant bone tumors of proximal tibia[J]. Yixue Xinzhi Zazhi, 2020, 30(4): 260-264. DOI: 10.12173/j.issn.1004-5511.2020.04.02.[Article in Chinese]

  • Abstract
  • Full-text
  • References
Abstract

Objective  To explore the difference between rotationally stable prosthesis and hinge prosthesis in the treatment of malignant bone tumors in proximal tibia, and to provide reference for practical use. 

Methods  Clinical data of 60 patients with proximal tibial bone malignancy treated with two different types of prosthesis in our hospital from June 2015 to June 2019 were retrospectively analyzed and divided into control group and study group. Thirty patients received simple hinge prosthesis replacement as the control group and 30 patients received Rotating stable prosthesis replacement as the research group. 

Results  Before treatment, there was no significant difference in knee joint function score between the two groups (P > 0.05); after treatment, the score of study group was (23.27±2.12) and control group was (19.13±4.52), which were significantly higher than before, with t values were 10.811 and 3.713, respectively (P < 0.05); and after treatment, the score of study group was significantly higher than control group, t values was 4.542(P < 0.05). The scores of social activities, physical activities, emotions, pain, sleep and energy in the study group were (27.25±3.16), (41.17±2.59), (20.18±2.13), (30.26±4.15), (25.18±2.19), (33.25±3.47), respectively, lower than control group, with t values of 4.609, 13.565, 7.724, 6.629, 19.632 and 5.539, respectively (P < 0.05). In study group, there were only 3 cases with tumors recurrence and 1 case with intra-articular hemorrhage, the incidence rate was 13.33%, which was significantly lower than 40% in control group, and χ2 was 4.176, the difference was statistically significant (P < 0.05). 

Conclusion  Rotary stable prosthesis can effectively improve the recovery of knee joint function, the quality of life and reduce complications, which is worthy of clinical application. However, it is worth noting that due to the possibility of recurrence, indications should be strictly observed in the selection of limb salvage surgery.

Full-text
Please download the PDF version to read the full text: download
References

1.徐明, 郑凯, 于秀淳, 等. 瘤型膝关节假体置换治疗胫骨近端骨巨细胞瘤多中心回顾性研究[J]. 中国骨与关节杂志, 2017, 6(2): 87-91. DOI: 10.3969/j.issn.2095-252X.2017.02.003. [Xu M, Zheng K, Yu XC, et al. Endoprosthetic replacement of the proximal tibia for giant cell tumor of bone: a multicenter retrospective study[J]. Chinese Journal of Bone and Joint, 2017, 6(2): 87-91.]

2.张铎安, 熊永发, 郭朝堂, 等. 可旋转稳定型假体与单纯铰链型假体治疗胫骨近端恶性骨肿瘤的临床对照研究[J]. 实用癌症杂志, 2017, 32(6): 1028-1030. DOI: 10.3969/j.ssn.001-930.017.6.4. [Zhang DA, Xiong YF, Guo CT, et al. Comparison of the spin stabilized prosthesis and simple hinge prosthesis in treatment of proximal tibia malignant bone tumor[J]. The Practical Journal of Cancer, 2017, 32(6): 1028-1030.]

3.刘剑帆, 罗毅, 徐学政, 等. 人工髋关节置换术治疗股骨近端骨肿瘤的疗效及安全性分析[J]. 中国现代医生, 2017(8): 77-79. [Liu JF, Luo Y, Xu XZ, et al. Analysis of the efficacy and safety of artificial hip replacement in the treatment of proximal femoral bone tumor[J]. China Modern Doctor, 2017(8): 77-79.]

4.Streitbuerger A, Henrichs M, Gosheger G, et al. Improvement of the shoulder function after large segment resection of the proximal humerus with the use of an inverse tumour prosthesis[J]. Int Orthop, 2015, 39(2): 355-361. DOI: 10.1007/s00264-014-2560-2.

5.史宇霞, 魏淑青. 人工全髋关节置换联合瘤段扩大切除对股骨近端骨肿瘤患者的疗效及QOL评分的影响[J]. 中国伤残医学, 2017, 25(24): 4-7. DOI: 10.13214/j.cnki.cjotadm.2017.24.003. [Shi YX, Wei SQ. Effect of total hip arthroplasty combined with extended tumor resection on the outcome and QOL score of patients with proximal femoral bone tumors[J]. Chinese Journal of Trauma and Disability Medicine, 2017, 25(24): 4-7.]

6.黄敏强, 丁焕文, 陈志源, 等. 3D打印导航模板辅助个性化非限制性肿瘤型假体重建术治疗膝关节周围恶性骨肿瘤的疗效[J]. 中国修复重建外科杂志, 2016(7): 815-821. DOI: 10.7507/1002-1892.20160167. [Huang MQ, Ding HW, Chen ZW, et al. Effect of three-dimensional printing navigation templates assisting reconstruction with personalized unprestricted total knee prosthesis for treating maliganant bone tumors around knees[J]. Chinese Journal of Reparative and Reconstructive Surgery, 2016(7): 815-821.]

7.侯磊, 李兴方, 程远娟, 等. 首例3D打印技术应用于表面膝代替铰链膝人工肿瘤假体置换术中的配合体会[J]. 吉林医学, 2016(2): 486-487. DOI: 10.3969/j.issn.1004-0412.2016.02.123. [Hou L, Li XF, Chen YJ, et al. The first case of 3D printing technology applied to surface knee instead of hinge knee artificial tumor prosthesis replacement operation experience[J]. Jilin Medical Journal, 2016(2): 486-487.] 

8.江正, 尹宗生, 胡勇, 等. 旋转铰链式人工假体置换:治疗股骨远端恶性骨肿瘤后肢体功能和生存率评价[J]. 中国组织工程研究, 2014, 18(4): 523-528. DOI: 10.3969/j.issn.2095-4344.2014.04.006. [Jiang Z, Yin ZS, Hu Y, et al. Rotating hinge prosthesis replacement for treatment of malignant bone tumors of the distal femur: evaluation of limb function and survival rate[J]. Chinese Journal of Tissue Engineering Research, 2014, 18(4): 523-528.]

9.Collins M, Wilhelm M, Conyers R, et al. Benefits and adverse events in younger versus older patients receiving neoadjuvant chemotherapy for osteosarcoma: findings from a meta-analysis[J]. J Clin Oncol, 2013, 31(18): 2303-2312. DOI: 10.1200/JCO.2012.43.8598.

10.马文学. 可旋转稳定型假体与单纯铰链型假体治疗胫骨近端恶性骨肿瘤的临床疗效比较[J]. 中华肿瘤防治杂志, 2016, 23(S1): 210-211. [Ma WX. Comparison of clinical efficacy between rotatable and stable prosthesis and hinged prosthesis in the treatment of malignant bone tumors of the proximal tibia[J]. Chinese Journal of Cancer Prevention and Treatment, 2016, 23(S1): 210-211.]

11.陈森, 李建平, 彭昊, 等. 可旋转稳定型假体与单纯铰链型假体治疗胫骨近端恶性骨肿瘤的临床疗效比较[J]. 中国矫形外科杂志, 2014, 22(2): 173-175. DOI: 10.3977/j.issn.1005-8478.2014.02.15. [Chen S, Li JP, Peng H, et al. Comparison of clinical efficacy between rotatable and stable prosthesis and hinged prosthesis in the treatment of malignant bone tumors of the proximal tibia[J]. Orthopedic Journal of China, 2014, 22(2): 173-175.]