Welcome to visit Zhongnan Medical Journal Press Series journal website!

The association between sleep duration, overweight/obesity, and multimorbidity among primary care medical staff

Published on Sep. 26, 2025Total Views: 37 timesTotal Downloads: 11 timesDownloadMobile

Author: JIANG Hong 1 LEI Haoyuan 2 GENG Hui 1 HE Dandan 3 ZHANG Yanxiu 1 MA Mao 1

Affiliation: 1. Department of Health Management, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China 2. Office of Discipline Construction, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China 3. Ministry of Science and Technology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China

Keywords: Multimorbidity Sleep duration Overweight/obesity Medical staff of primary health service institutions

DOI: 10.12173/j.issn.1004-5511.202502038

Reference: Jiang H, Lei HY, Geng H, He DD, Zhang YX, Ma M. The association between sleep duration, overweight/obesity, and multimorbidity among primary care medical staff[J]. Yixue Xinzhi Zazhi, 2025, 35(9): 1004-1010. DOI: 10.12173/j.issn.1004-5511.202502038. [Article in Chinese]

  • Abstract
  • Full-text
  • References
Abstract

Objective  To investigate the association of sleep duration and overweight/obesity with the risk of multimorbidity among primary care medical staff.

Methods  Medical staff of primary health service institutions in Shaanxi Province were selected as the study subjects using the convenient cluster sampling method. Information about personal life behavior was collected via online questionnaire. The association between sleep duration, overweight/obesity and chronic diseases and multimorbidity was analyzed.

Results  A total of 3,483 primary care medical staff were included. The prevalence rate of multimorbidity in the present study was 7.78%. Multivariate ordinal Logistic regression analysis showed that poor sleep (<7 h or >9 h) [OR=1.31, 95%CI (1.05, 1.64)] and overweight/obesity (BMI≥24.0 kg/ m2) [OR=2.06, 95%CI (1.69, 2.52)] were associated with increased risk of multimorbidity. A U-shaped curve was observed between sleep time and the risk of multimorbidity by using the cubic spline model, with the participants who slept 7~9 h had the lowest risk of multimorbidity and BMI showed a linear association with the risk of such disease. The results of joint analysis revealed that optimal sleep combined with overweight/obesity [OR=2.11, 95%CI (1.70, 2.64)] and suboptimal sleep combined with overweight/ obesity [OR=3.12, 95%CI (2.28, 4.25)] were significantly associated with an increased risk of multimorbidity compared with those with optimal sleep combined with lean/normal weight.

Conclusion  Suboptimal sleep, overweight/obesity and their interactions are significantly associated with an increased risk of multimorbidity, and therefore, improve sleep and establish a healthy lifestyle might be a potential useful strategy for multimorbidity prevention among medical staff of primary health service institutions.

Full-text
Please download the PDF version to read the full text: download
References

1.Su B, Li D, Xie J, et al. Chronic disease in China: geographic and socioeconomic determinants among persons aged 60 and older[J]. J Am Med Dir Assoc, 2023, 24(2): 206-212. DOI: 10.1016/j.jamda.2022.10.002.

2.Liu S, Li Y, Zeng X, et al. Burden of cardiovascular diseases in China, 1990-2016: findings from the 2016 Global Burden of Disease Study[J]. JAMA Cardiol, 2019, 4(4): 342-352. DOI: 10.1001/jamacardio.2019.0295.

3.DeCola P, Benton D, Peterson C, et al. Nurses' potential to lead in non-communicable disease global crisis[J]. Int Nurs Rev, 2012, 59(3): 321-330. DOI: 10.1111/j.1466-7657.2012.01006.x.

4.Faruque M, Barua L, Banik PC, et al. Prevalence of non-communicable disease risk factors among nurses and para-health professionals working at primary healthcare level of Bangladesh: a cross-sectional study[J]. BMJ Open, 2021, 11(3): e043298. DOI: 10.1136/bmjopen-2020-043298.

5.Kayaroganam R, Sarkar S, Satheesh S, et al. Profile of non-communicable disease risk factors among nurses in a tertiary care hospital in south India[J]. Asian Nurs Res (Korean Soc Nurs Sci), 2022, 16(4): 241-248. DOI: 10.1016/j.anr.2022.07.001.

6.郑虹, 齐振波, 徐杰, 等. 高龄老年睡眠质量和睡眠时长与糖尿病关系的研究[J]. 中国循证心血管医学杂志, 2024, 16(9): 1044-1047. [Zheng H, Qi ZB, Xu J, et al. Relationship among sleep quality,sleep duration and diabetes in elderly patients[J]. Chinese Journal of Evidence-Bases Cardiovascular Medicine, 2024, 16(9): 1044-1047.] DOI: 10.3969/j.issn.1674-4055. 2024.09.05.

7.Chen Y, Kartsonaki C, Clarke R, et al. Sleep duration and risk of stroke and coronary heart disease: a 9-year community-based prospective study of 0.5 million Chinese adults[J]. BMC Neurol, 2023, 23(1): 327. DOI: 10.1186/s12883-023-03367-4.

8.宋小玲,郑利,金菊珍,等. 40~65岁人群睡眠质量与动脉硬化的关联性研究[J]. 中国全科医学, 2025, 28(17): 2113-2118, 2126. [Song XL, Zheng L, Jin JZ, et al. Association between sleep quality and atherosclerosis among population aged 40-65 Years[J]. Chinese General Practice, 2025, 28(17): 2113-2118, 2126.] DOI: 10.12114/j.issn.1007-9572.2024.0530.

9.樊萌, 杨娅娟, 陶芳标, 等. 护士轮班与心血管代谢风险关联的研究进展[J]. 环境与职业医学, 2025, 42(4): 512-516. [Fan  M, Yang YJ, Tao FB, et al. Research progress on association between shift work and cardiometabolic risk in nurses[J]. Journal of Environmental & Occupational Medicine, 2025, 42(4): 512-516.] DOI: 10.11836/JEOM24359.

10.安洪鑫, 夏侯鸾达, 李云权, 等. 轮班工作与心脑血管疾病的孟德尔随机化研究[J]. 现代预防医学, 2024, 51(13): 2305-2311. [An HX, Xiahou LD, Li YQ, et al. Shift and cardiovascular and cerebrovascular diseases: Mendelian randomized study[J]. Modern Preventive Medicine, 2024, 51(13): 2305-2311.] DOI: 10.20043/j.cnki.MPM.202401174.

11.Pan XF, Wang L, Pan A. Epidemiology and determinants of obesity in China[J]. Lancet Diabetes Endocrinol, 2021, 9(6): 373-392. DOI: 10.1016/S2213-8587(21)00045-0.

12.Guo X, Gong S, Chen Y, et al. Lifestyle behaviors and stress are risk factors for overweight and obesity in healthcare workers: a cross-sectional survey[J]. BMC Public Health, 2023, 23(1): 1791. DOI: 10.1186/s12889-023-16673-w.

13.Mittal TK, Cleghorn CL, Cade JE, et al. A cross-sectional survey of cardiovascular health and lifestyle habits of hospital staff in the UK: do we look after ourselves[J]? Eur J Prev Cardiol, 2018, 25(5): 543-550. DOI: 10.1177/2047487317746320.

14.高旸, 许杰, 陈莉玲, 等. 重庆市30~79岁成人夜间睡眠时间与超重肥胖的关联性分析[J]. 中国慢性病预防与控制, 2025, 33(1): 51-55. [Gao Y, Xu J, Chen LL, et al. The correlation between sleep time and overweight and obesity in adults aged 30-79 years in Chongqing[J]. Chinese Journal of Prevention and Control of Chronic Diseases, 2025, 33(1): 51-55.] DOI: 10.16386/j.cjpccd.issn.1004-6194.20211112.0732.

15.Miller MA. Time for bed: diet, sleep and obesity in children and adults[J]. Proc Nutr Soc, 2025, 84(1): 45-52. DOI: 10.1017/S0029665123004846.

16.李游, 汪蝶, 王大珊, 等. 贵州省40~65岁人群睡眠质量与肥胖关联及晚睡和睡眠规律性效应修饰[J]. 中国预防医学杂志, 2025, 26(1): 15-20. [Li Y, Wang D, Wang DS, et al. Association between sleep quality and obesity in the 40-65 year-old population in Guizhou province and the modifying effects of late bedtime and sleep regularity[J]. Chinese Preventive Medicine, 2025, 26(1): 15-20.] DOI: 10.16506/j.1009-6639.2025.01.003.

17.健康中国行动推进委员会. 健康中国行动(2019—2030年): 总体要求、重大行动及主要指标[J]. 中国循环杂志, 2019, 34(9): 846-858. DOI: 10.3969/j.issn.1000-3614.2019.09.003.

18.中华人民共和国卫生部疾病预防控制司. 中国成人超重和肥胖症预防控制指南[M]. 北京: 人民卫生出版社, 2006: 1-36.

19.王司宇, 张卿, 王崇金, 等. 老年人慢病多病共患模式及管理研究进展[J]. 健康体检与管理, 2023, 4(4): 375-379. [Wang SY, Zhang Q, Wang CJ, et al. Research progress of chronic and multiple disease comorbidity model and management in the elderly[J]. Journal of Health Examination and Management, 2023, 4(4): 375-379. https://d.wanfangdata.com.cn/periodical/ChVQZXJpb2RpY2FsQ0hJMjAyNTA2MjISEWprdGp5dWdsMjAyMzA0MDEyGghxMTZkNG53Mg%3D%3D

20.Yin J, Jin X, Shan Z, et al. Relationship of sleep duration with all-cause mortality and cardiovascular events: a systematic review and dose-response Meta-analysis of prospective cohort studies[J]. J Am Heart Assoc, 2017, 6(9): e005947. DOI: 10.1161/JAHA.117.005947.

21.Cui H, Xu R, Wan Y, et al. Relationship of sleep duration with incident cardiovascular outcomes: a prospective study of 33,883 adults in a general population[J]. BMC Public Health, 2023, 23(1): 124. DOI: 10.1186/s12889-023-15042-x.

22.Papatriantafyllou E, Efthymiou D, Zoumbaneas E, et al. Sleep deprivation: effects on weight loss and weight loss maintenance[J]. Nutrients, 2022, 14(8): 1549. DOI: 10.3390/nu14081549.

23.Taheri S, Lin L, Austin D, et al. Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index[J]. PLoS Med, 2004, 1(3): 62. DOI: 10.1371/journal.pmed.0010062.

24.Nono Nankam PA, Nguelefack TB, Goedecke JH, et al. Contribution of adipose tissue oxidative stress to obesity-associated diabetes risk and ethnic differences: focus on women of African ancestry[J]. Antioxidants (Basel), 2021, 10(4): 622. DOI: 10.3390/antiox10040622.

25.向凤, 曹学华, 胡婉琴, 等. 超重肥胖儿童非酒精性脂肪性肝病患病率及影响因素的Meta分析[J]. 数理医药学杂志, 2024, 37(12): 935-946. [Xiang F, Cao XH, Hu WQ, et al. Prevalence and risk factors of nonalcoholic fatty liver disease in overweight and obese children: a Meta-analysis[J]. Journal of Mathematical Medicine, 2024, 37(12): 935-946.] DOI: 10.12173/j.issn.1004-4337.202407113.

26.Najjar SM, Abdolahipour R, Ghadieh HE, et al. Regulation of insulin clearance by non-esterified fatty acids[J]. Biomedicines, 2022, 10(8): 1899. DOI: 10.3390/biomedicines 10081899.

27.Heymsfield SB, Wadden TA. Mechanisms, pathophysiology, and management of obesity[J]. N Engl J Med, 2017, 376(3): 254-266. DOI: 10.1056/NEJMra1514009.