Ischemic hepatitis (IH), also known as hypoxic hepatitis (HH) or shock liver, is a clinical syndrome characterized by a rapid, significant rise in the plasma ami-notransferase level and centrilobular liver cell necrosis. IH has a strong relationship with cardiac, respiratory and circulatory failure that all result in poor perfusion and oxygen delivery to the liver. It's not rare in intensive care units (ICU). The pathogenesis of IH is complex and early diagnosis is difficult. Meanwhile there are still no clear diagnostic criteria and specific treatment options for IH, which results in a poor prognosis and high mortality rate. This review provides an overview of the epidemiology, etiology, pathogenesis and the advance of current treatment of IH, in order to deepen the clinical knowledge of this disease, promote early recognition and timely treatment, and improve its diagnosis and treatment.

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