Experimental diagnostics is a crucial component of medical education, setting high demands on students' theoretical knowledge and practical skills. However, traditional teaching models is no longer suitable for the evolving needs of modern education.Through an in-depth analysis of the current state of experimental diagnostics education, this study identifies several issues inherent in traditional teaching models, such as a lack of diversity in teaching methods, insufficient emphasis on practical training, and inadequate development of experimental skills. The introduction of the college students' innovation and entrepreneurship training program offers a novel approach to teaching reform. Project-based practical teaching has shown significant improvements in students' practical abilities, research-oriented thinking, and teamwork skills. The study proposes a series of teaching reform recommendations, including the implementation of project-based teaching models, integration of multidisciplinary content, and enhancement of self-directed learning abilities, with the goal of comprehensively improving students' overall competence and innovation potential. These reform measures are anticipated to effectively advance the teaching of experimental diagnostics, foster students' innovative spirit and practical skills, and provide an effective pathway for training high-level innovative medical talents for the new era.

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