Preeclampsia (PE) is a vascular disease characterized by hypertension and proteinuria during pregnancy and is one of the leading causes of maternal and fetal mortality. The placenta plays a central role in the pathogenesis of PE, but the mechanism of its occurrence has not been elucidated. Non-coding RNAs have numerous functions, and it has been shown that long non-coding RNA (lncRNA) and microRNA (miRNA) can in-fluence the development and progression of PE by affecting placental trophoblast cell function. To this end, this study reviews the research progress of lncRNA and miRNA in the pathogenesis of PE, and provides a reference for the prevention and treatment of PE.
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Research progress of long non-coding RNA and miRNA in pathogenesis of preeclamp-sia
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