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The application of antimicrobial agents in regenerative endodontic procedures

Published on Nov. 25, 2022Total Views: 648 timesTotal Downloads: 354 timesDownloadMobile

Author: Xiao-Yi ZHONG 1 Bei-Bei XIE 2

Affiliation: 1. Comprehensive Care Clinc, College of Stomatology, Guangxi Medical University, Nanning, 530021, China 2. Department of Conservative Dentistry & Endodontics, College of Stoma-tology, Guangxi Medical University, Nanning, 530021, China

Keywords: Immature teeth with pulp necrosis Regeneration endodontic procedures Triple antibiotic paste Double antibotic paste Calcium hydroxide

DOI: 10.12173/j.issn.1004-5511.202207017

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Regenerative endodontics is one of the main therapies for immature teeth with pulp necrosis. Its key goals involve controlling infection in the root canal and promoting the proliferation and differentiation potential of apical stem cells.. Therefore, it is essential to choose appropriate antimicrobial therapeutics for clinical application, which can control the infection of immature teeth and protect apical stem cells thus promoting the con-tinued development of the root, preserving teeth and maintaining the integrity of den-tition after treatment. This paper reviews the antibacterial characteristics of common root canal disinfectant drugs used in endodontic regeneration procedures, the biocompatibility of apical stem cells, medication methods and the clinical application efficacy of both, so as to provide a reference for the selection of antimicrobial agents in clinical treatment.

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