Welcome to visit Zhongnan Medical Journal Press Series journal website!

Status of refractive development among children and adolescents aged 6~16 in Fuzhou

Published on Dec. 25, 2022Total Views: 1928 timesTotal Downloads: 887 timesDownloadMobile

Author: Jia-Jia LIN 1, 2, 3 Chun-Min LIU 4

Affiliation: 1. Eye Institute and Affiliated Xiamen Eye Center of Xiamen University, Xiamen 361003, Fujian Province, China 2. Fujian Provincial Key Laboratory of Corneal & Ocular Surface Diseases, Xiamen 361003, Fujian Province, China 3. Fuzhou Eye Hospital, Fuzhou 350007, China 4. Shenzhen Huaxia Eye Hospital, Shenzhen 518034, Gungdong Prov-ince, China

Keywords: Myopia Cycloplegic refraction Spherical equivalent Axial length Corneal radius Axial length/Corneal radius ratio

DOI: 10.12173/j.issn.1004-5511.202203031

Reference: Lin JJ, Liu CM. Status of refractive development among children and adolescents aged 6~16 in Fuzhou[J]. Yixue Xinzhi Zazhi, 2022, 32(6): 434-440. DOI: 10.12173/j.issn.1004-5511.202203031.[Article in Chinese]

  • Abstract
  • Full-text
  • References
Abstract

Objective  To investigate the status of refractive development among children and ado-lescents aged 6-16 in Fuzhou. 

Method  From January 1 to December 31, 2021, we collected data on children and adolescents aged 6-16 years in Fuzhou, which included spherical equivalent (SE) after cycloplegia, axial length (AL), corneal radius (CR) and calculated the AL/CR ratio, and performed correlation analysis. 

Results  A total of 2,888 patients were included, and the right eye was used for all analyses. The differences in SE after cy-cloplegia, AL and the AL/CR ratio in different age groups were statistically significant (P<0.001). There was a negative correlation between SE after cycloplegia and age (r=-0.356, P<0.01), and a positive correlation between AL, AL/CR ratio and age (r=0.413, P<0.01; r=0.425, P<0.01). CR remained stable with age, and there was no sig-nificant correlation between CR and age (r=0.035, P>0.05). There were significant differences in AL, CR and AL/CR ratio between different genders (P<0.001), females had shorter AL, smaller CR, steeper corneal curvature, and slightly lower AL/CR ratio than males. The differences in AL and AL/CR ratio between different refractive state groups were statistically significant (P<0.001), AL and AL/CR ratio were positively correlated with the de-gree of myopia (r=0.636, P<0.01; r=0.767, P<0.01). There was no statistical significance for the difference in CR between different refractive state groups (P>0.05), but there were statistically significant differences in CR be-tween different myopia groups (P<0.001), CR was negatively correlated with the degree of myopia (r=-0.067, P<0.01), CR in the high myopia group was smaller than that in the moderate  and low myopia groups, i.e. the corneal curvature was steeper. 

Conclusion  The refractive status of children and adolescents aged 6-16 years in Fuzhou, drifted towards myopia with increasing age, AL and the AL/CR ratio showed an increasing trend, while the CR remained basically stable. 

Full-text
Please download the PDF version to read the full text: download
References

1.Holden BA, Fricke TR, Wilson DA, et al. Global prevalence of myopia and high myopia and temporal trends from 2000 through 2050[J]. Ophthalmology, 2016, 123: 1036-1042. DOI: 10.1016/j.ophtha.2016.01.006.

2.国家卫生健康委员会. 国家卫生健康委员会2021年7月13日新闻发布会文字实录[EB/OL]. (2021-07-13) [2022-03-03]. http://www.nhc.gov.cn/xcs/s3574/202107/2fef24a3b77246fc9fb36dc8943af700.shtml. 

3.Haarman AEG, Enthoven CA, Tideman JWL, et al. The complications of myopia: a review and meta-analysis[J]. Invest Ophthalmol Vis Sci, 2020, 61(4): 49. DOI: 10.1167/iovs.61.4.49.

4.Modjtahedi BS, Abbott RL, Fong DS, et al. Reducing the global burden of myopia by delaying the onset of myopia and reducing myopic progression in children: the academy's task force on myopia[J]. Ophthalmology, 2021, 128(6): 816-826. DOI: 10.1016/j.ophtha.2020.10.040.

5.Hu Y, Ding X, Guo X, et al. Association of age at myopia onset with risk of high myopia in adulthood in a 12-year follow-up of a Chinese cohort[J]. JAMA Ophthalmol, 2020, 138(11): 1129-1134. DOI: 10.1001/jamaophthalmol.2020.3451.

6.Sankaridurg PR, Holden BA. Practical applications to modify and control the development of ametropia[J]. Eye (Lond), 2014, 28(2): 134-141. DOI: 10.1038/eye.2013.255.

7.中华医学会眼科学分会斜视与小儿眼科学组. 中国儿童睫状肌麻痹验光及安全用药专家共识(2019年)[J]. 中华眼科杂志, 2019, 55(1): 7-12. [Chinese Association for Pediatric Ophthalmology and Stra-bismus. Expert consensus on optometry after cycloplegia and safe drug use (2019)[J]. Chinese Journal of Ophthalmology, 2019, 55(1): 7-12.] DOI: 10.3760/cma.j.issn.0412-4081.2019.01.003.

8.Jong M, Resnikoff S, Tan KO, 等. 亚洲近视管理共识[J]. 中华眼视光学与视觉科学杂志, 2022, 24(3): 161-169.[Jong M, Resnikoff S,Tan KO, et al. Consensus on myopia management for Asia[J]. Chinese Journal of Optometry Ophthalmology and Visual Science, 2022, 24(3): 161-169.] DOI: 10.3760/cma.j.cn115909-20211125-00459.

9.Sanz Diez P, Yang LH, Lu MX, et al. Growth curves of myopia-related parameters to clinically monitor the refractive development in Chinese schoolchildren[J]. Graefes Arch Clin Exp Oph-thalmol, 2019, 257(5): 1045-1053. DOI: 10.1007/s00417-019-04290-6.

10. He X, Sankaridurg P, Naduvilath T, et al. Normative data and percentile curves for axial length and axial length/corneal curvature in Chinese children and adolescents aged 4-18 years[J]. Br J Ophthalmol, 2021. DOI: 10.1136/bjophthalmol-2021-319431.

11. Momeni-Moghaddam H, Hashemi H, Zarei-Ghanavati S, et al. Four-Year change in ocular bi-ometric components and refraction in schoolchildren: a cohort study[J]. J Curr Ophthalmol, 2018, 31(2): 206-213. DOI: 10.1016/j.joco. 2018.10.009.

12. Tideman JWL, Polling JR, Vingerling JR, et al. Axial length growth and the risk of developing myopia in European children[J]. Acta Ophthalmol, 2018, 96(3): 301-309. DOI: 10.1111/aos.13603.

13. Rauscher FG, Francke M, Hiemisch A, et al. Ocular biometry in children and adolescents from 4 to 17 years: a cross-sectional study in central Germany[J]. Ophthalmic Physiol Opt, 2021, 41(3): 496-511. DOI: 10.1111/aos.13603.

14. 魏文斌, 董力. 重视病理性近视眼的眼底并发症 提升病理性近视眼综合防治水平[J]. 中华眼科杂志, 2021, 57(6): 401-405. [Wei WB, Dong L. Paying attention to the fundus complications and improving the prevention and treatment of pathological myopia[J]. Chinese Journal of Ophthalmology, 2021, 57(6): 401-405.] DOI: 10.3760/cma.j.cn112142-20210114-00035.

15. 中华预防医学会公共卫生眼科分会. 中国学龄儿童眼球远视储备、眼轴长度、角膜曲率参考区间及相关遗传因素专家共识(2022年)[J]. 中华眼科杂志, 2022, 58(2): 96-102. [Public Health Ophthalmology Branch of Chinese Preventive Medicine Association. Chinese expert consensus on the refer-ence interval of ocular hyperopia reserve, axial length, corneal curvature and genetic factors in school age children (2022)[J]. Chinese Journal of Ophthalmology, 2022, 58(2): 96-102.] DOI: 10.3760/cma.j.cn112142-20210603-00267.

16. Morgan IG, Wu PC, Ostrin LA, et al. IMI risk factors for myopia[J]. Invest Ophthalmol Vis Sci, 2021, 62(5): 3. DOI: 10.1167/iovs.62.5.3.

17. Jonas JB, Ang M, Cho P, et al. IMI prevention of myopia and its progression[J]. Invest Oph-thalmol Vis Sci, 2021, 62(5): 6. DOI: 10.1167/iovs.62.5.6.

18. Gifford KL, Richdale K, Kang P, et al. IMI clinical management guidelines report[J]. Invest Ophthalmol Vis Sci, 2019, 60(3): M184-M203. DOI: 10.1167/iovs.18-25977.

19. 向棹宇, 林秋蓉,许琰, 等. 3~12岁儿童晶状体屈光力变化趋势及其影响因素分析[J]. 中华实验眼科杂志, 2021, 39(6): 550-556. [Xiang ZY, Lin QR, Xu Y, et al. Analysis of lens power and its influencing factors in children aged 3-12 years[J]. Chinese Journal of Experimental Ophthalmology, 2021, 39(6): 550-556.] DOI: 10.3760/cma.j.cn115989-20200304-00138.

20. Foo VH, Verkicharla PK, Ikram MK, et al. Axial length/corneal radius of curvature ratio and myopia in 3-year-old children[J]. Transl Vis Sci Technol, 2016, 5(1): 5. DOI: 10.1167/tvst.5.1.5.