Welcome to visit Zhongnan Medical Journal Press Series journal website!
Zhongnan Medical Journal Press Series of Journals Center for Evidence-Based and Translational Medicine of Wuhan University

The title
  • The title
  • The keywords
  • The author
Submit中文版

HomeArticlesVol 32,2022 No.2Detail

Research on the promotion of implementation of clinical practice guidelines(IV): knowledge extraction, storage and example presentation of a knowledge garph for clinical guidelines for Traditional Chinese Medicine/Integrated Traditional Chinese and Western Medicine

Published on Apr. 25, 2022Total Views: 7973 timesTotal Downloads: 3068 timesDownloadMobile

Author: Yi-Bei SI 1 Jing GUO 2 Yong-Bo WANG 3 Xu-Hui LI 3 Qiao HUANG 3 Jia-Ying WANG 4 Ying-Hui JIN 3 Hong-Cai SHANG 5

Affiliation: 1. The Second Clinical College, Wuhan University, Wuhan 430071, China 2. Acupuncture and Rehabilitation De-partment, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China 3. Center for Evidence-Based and Translational Medicine, Zhongnan Hospital of Wuhan University, Wuhan 430071, China 4. National Drug Clinical Trials Institution, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wu-xi 214000, Jiangsu Province, China 5. Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China

Keywords: Traditional Chinese Medicine Integrated Traditional Chinese and Western Medicine Clinical guideline Knowledge graph Neo4j

DOI: 10.12173/j.issn.1004-5511.202112007

Reference: Si YB, Guo J, Wang YB, Li XH, Huang Q, Wang JY, Jin YH, Shang HC. Research on the promotion of implementation of clinical practice guidelines(IV): knowledge extraction, storage and example presentation of a knowledge garph for clinical guidelines for Traditional Chinese Medicine/Integrated Traditional Chinese and Western Medicine[J]. Yixue Xinzhi Zazhi, 2022, 32(2): 99-107. DOI: 10.12173/j.issn.1004-5511.202112007.[Article in Chinese]

  • Abstract
  • Full-text
  • References
Abstract

In this study, based on the characteristics of Traditional Chinese Medicine (TCM) diagnosis and treatment and TCM clinical guidelines, knowledge extraction and knowledge storage were carried out to construct a knowledge graph depicting Traditional Chinese Medicine/Integrated Traditional Chi-nese and Western Medicine (IM) clinical guidelines using the "Guidelines of the Traditonal Chinese Medicine management of stable angina pectoris in coronary artery disease" as an example. This enabled us to further test the operability and rationality of the application of knowledge graph technology to the field of TCM/IM guidelines. The graph was constructed using the design of the concept layer and the da-ta layer, extracting entities and relationships from the guidelines, sorting them into the entity database and triple relationship databases for knowledge importation, using neo4j for knowledge storage, re-trieving and verifying the correctness of the knowledge graph, and completing the visual display. The methods used in constructing the knowledge graph for this clinical guideline also provides a template for the construction of knowledge graphs for TCM/IM clinical guidelines for other diseases.

Full-text
Please download the PDF version to read the full text: download
References

1.中华中医药学会心血管病分会. 冠心病稳定型心绞痛中医诊疗指南[J]. 中医杂志, 2019, 60(21): 1880-1890. [China Association of Chinese Medicine Cardiovascular Disease Section. Guide-lines of the Traditonal Chinese Medicine for stable angina pectoris in coronary artery dis-ease[J]. Journal of Traditional Chinese Medicine, 2019, 60(21): 1880-1890.] DOI: 10.13288/j.11-2166/r.2019.21.015.

2.Stothers JAM, Nguyen A. Can Neo4j replace postgreSQL in healthcare?[J]. AMIA Jt Summits Transl Sci Proc, 2020, 2020: 646-653. https://pubmed.ncbi.nlm.nih.gov/32477687/.

3.赵凯, 王华星, 施娜, 等. 基于Neo4j桂枝汤类方知识图谱的研究与实现[J]. 世界中医药, 2019, 14(10): 2636-2639, 2646. [Zhao K, Wang HX, Shi N, et al. Study and implementation on knowledge graph of guizhi decoction associated formulas based on Neo4j[J]. World Chinese Medicine, 2019, 14(10): 2636-2639, 2646.] DOI: 10.3969/j.issn.1673-7202. 2019.10.019.

4.刘燕, 贾志杰, 闫利华, 等. 知识图谱研究综述[J].赤峰学院学报(自然科学版), 2021, 37(4): 33-36. [Liu Y, Jia ZJ, Yan LH, et al. Review of knowledge mapping[J]. Journal of Chifeng University (Natu-ral Science Edition), 2021, 37(4): 33-36.] DOI: 10.3969/j.issn.1673-260X.2021.04.010.

5.侯梦薇, 卫荣, 陆亮, 等. 知识图谱研究综述及其在医疗领域的应用[J].计算机研究与发展, 2018, 55(12): 2587-2599. [Hou MW, Wei R, Lu L, et al. Research review of knowledge graph and its applica-tion in medical domain[J]. Journal of Computer Research and Development, 2018, 55(12): 2587-2599.] DOI: 10.7544/issn1000-1239.2018.20180623.

6.Hesketh T, Zhu WX. Health in China. Traditional Chinese Medicine: one country, two sys-tems[J]. BMJ, 1997, 315(7100): 115-117. DOI: 10.1136/bmj.315.7100.115.

7.孙华君, 李海燕, 聂莹, 等. 知识图谱及其在中医药领域应用研究进展[J].世界科学技术-中医药现代化, 2020, 22(6): 1969-1974. [Sun HJ, Li HY, Nie Y, et al. Research progress in knowledge graph and its application in the field of TCM[J]. World Science and Technology-Modernization of Tradi-tional Chinese Medicine, 2020, 22(6): 1969-1974.] DOI: 10.11842/wst. 20190429007.

8.王菁薇, 肖莉, 晏峻峰. 基于Neo4j的《伤寒论》知识图谱构建研究[J]. 计算机与数字工程, 2021, 49(2): 264-267, 396. [Wang JW, Xiao L, Yan JF. Research on construction of knowledge graph of treatise on febrile diseases based on Neo4j[J]. Computer and Digital Engineering, 2021, 49(2): 264-267, 396.] DOI: 10.3969/j.issn.1672-9722. 2021.02.007.

9.聂莉莉, 李传富, 许晓倩, 等. 人工智能在医学诊断知识图谱构建中的应用研究[J]. 医学信息学杂志, 2018, 39(6): 7-12. [Nie LL, Li CF, Xu XQ. Study on application of artificial intelligence in the building of medical diagnosis knowledge graph[J]. Journal of Medical Informatics, 2018, 39(6): 7-12.] DOI: 10.3969/j.issn.1673-6036.2018.06.002. 

10.曹馨宇, 谢琪, 周洪伟, 等. 面向中医养生的冠心病知识本体构建研究[J].世界科学技术-中医药现代化, 2016, 18(4): 683-687. [Cao XY, Xie Q, Zhou HW, et al. Constructing knowledge ontology of coronary artery disease based on Traditional Chinese Medicine health preservation[J]. World Science and Technology-Modernization of Traditional Chinese Medicine, 2016, 18(4): 683-687.] DOI: 10.11842/wst.2016.04.021.

Popular Papers
© 2022 - 2024 Zhongnan Medical Journal Press of Zhongnan Hospital of Wuhan University|Support: Yufu Technology
About NM | Contact us