Objective  To systematically evaluate the effectiveness of parent-based psychological intervention(PBPI) in the treatment of adolescents with depressive disorders.

Methods  CNKI, Wanfang, VIP, PubMed, Web of Science, Embase, and PsyINFO databases were searched from the inception to April 17, 2024, to obtain randomized controlled trials for psychological interventions for parents of adolescents with depressive disorders. RevMan 5.1 and Stata 14.0 software were used to analyze the data.

Results  A total of 11 articles with 932 patients were included. The Meta-analysis results showed that compared to the control group, PBPI could significantly reduce the levels of depression in adolescents with depression disorders [SMD=-0.77, 95%CI(-1.39, -0.15), P=0.02]. The effects were statistically significant when using the Hamilton Depression Scale 24-item version [SMD=-3.00, 95%CI(-4.10, -1.90), P<0.001] and the Beck Depression Inventory [SMD=-5.21,95%CI(-9.57, -0.85), P=0.02], the number of interventions exceeded 8 times [SMD=-0.50, 95%CI(-0.93, -0.06), P=0.03], using conventional controls [SMD=- 1.08, 95%CI(-1.81, -0.35), P=0.004], results assessed by others [SMD=- 0.87, 95%CI(- 1.71, -0.04), P=0.04], and when the intervention was conducted on the Chinese population [SMD=-1.56, 95%CI(-2.46, -0.66), P<0.001]. When compared with the control group, PBPI could significantly reduce the anxiety levels [SMD=-0.78, 95%CI(-1.14, -0.43), P<0.001], but could not reduce the self-harming behaviors [SMD=-1.24, 95%CI(-2.97, 0.30), P=0.12] and suicidal ideation [SMD=- 0.04, 95%CI(-0.34, 0.25), P=0.78].

Conclusion  PBPI can reduce the depression and anxiety levels in adolescents with depressive disorders, but it does not show a significant effect on self-harming behaviors or suicidal ideation. Due to the limitations in the number of studies, this conclusion needs further validation through larger sample sizes and higher-quality studies.

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