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Meta-analysis of incidence and influencing factors of dry skin in the elderly

Published on Jan. 31, 2024Total Views: 377 timesTotal Downloads: 247 timesDownloadMobile

Author: XIAO Chunye 1 PENG Yuxin 1 WANG Bingyao 1 FU Guanglei 2

Affiliation: 1. School of Nursing, Jinan University, Guangzhou 510632, China 2. Department of Infectious Diseases, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China

Keywords: Old people Dry skin Influencing factors Incidence Meta- analysis

DOI: 10.12173/j.issn.1004-5511.202310097

Reference: Xiao CY, Peng YX, Wang BY, Fu GL. Meta-analysis of incidence and influencing factors of dry skin in the elderly[J]. Yixue Xinzhi Zazhi, 2024, 34(1): 43-52. DOI: 10.12173/j.issn.1004-5511.202310097.[Article in Chinese]

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Abstract

Objective  To systematically evaluate the status and influencing factors of dry skin in the elderly.

Methods  The PubMed, Embase, Web of Science, CNKI, CBM, VIP and Wan-Fang databases were systematically searched from the establishment of each database to June, 2023. Literature screening, quality evaluation, and information extraction were conducted independently by two researchers, and Meta-analysis of incidence and influencing factors was performed using Stata 17.0 software.

Results  19 literatures were included, all cross-sectional studies, including 69,260 elderly patients, of whom 24,580 had dry skin. The results of Meta-analysis showed that the incidence of dry skin in the elderly was 49%[95CI%(36%, 61%)]. The results of subgroup analysis showed that the incidence of dry skin was higher among elderly people in men, from nursing institutions and in the European regions. The prevalence of dry skin in the elderly was also relatively high in the literature with a sample size<1,000, and a publication year between 2012 and 2017, with the highest prevalence of dry skin in the lower extremity areas of the elderly, followed by the upper extremities, the trunk, and the head and face.

Results of Meta-analysis showed that gender [OR=0.15, 95%CI(0.04, 0.25), P=0.005], age [OR=1.43, 95%CI(1.05, 1.94), P=0.021], diabetes mellitus [OR=1.18, 95%CI(1.13, 1.23), P<0.001], cardiovascular disease [OR=1.15, 95%CI(1.11, 1.20), P<0.001], pruritus[OR=9.65, 95%CI(6.36,14.64), P<0.001], diuretics [OR=1.22, 95%CI(1.10, 1.35), P<0.001] and antibiotics [OR=1.08, 95%CI(1.03, 1.13), P<0.001] were the influential factors in the development of dry skin in the elderly.

Conclusion  Higher prevalence of dry skin in the elderly, with age, gender, diabetes, cardiovascular disease, itchy skin, and the use of diuretics and antibiotics as influencing factors for dry skin in the elderly. However, this study also has some limitations, which should be verified by further high-quality studies in the future.

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