Objective  To explore the effect of applying an information management system to the prevention and control of multidrug-resistant organisms (MDROs) infection.

Methods  The implementation rate of MDROs prevention and control measures, the incidence of nosocomial MDRO infections, and the detection rate of environmental MDROs were compared and analyzed for medical staff before and after the implementation of the information management system in Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology. 

Results  After the implementation of the information management system, except the compliance rate among technicians for "Wearing isolation gowns during close-range operations", the implementation rates of other MDROs prevention and control measures for doctors, nurses and technicians were significantly higher than before (P<0.001). However, the implementation rate among doctors for "Following hand hygiene procedures strictly", "Wearing isolation gowns dur-ing close-range operations", "Finally arranging ward rounds or diagnosis and treatment operations" and for nurses "Isolating patients and special items of equipment " and "Wearing isolation gowns during close-range operations" and for technicians "Wearing isolation gowns during close-range operations" were still lower than 80%. The incidence of nosocomial MDRO infections had decreased significantly from 0.34% before to 0.25% after the implementation of the information management (P<0.001). The detection rates of methicillin-resistant staphylococcus aureus, car-bapenem-resistant acinetobacter baumannii and carbapenem-resistant enterobacter on the ward environmental sur-faces were significantly lower than before (P<0.001). 

Conclusion  The application of the information manage-ment system had a significant effect on the management of MDROs, thus providing strong support for its use in the prevention and control of the spread and outbreak of MDROs, as well as ensuring the quality and safety of medical care.

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