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Progress in the diagnosis of immunoglobulin G4-related coronary arteritis

Published on Sep. 18, 2021Total Views: 3465 timesTotal Downloads: 2213 timesDownloadMobile

Author: Lai-Sheng MIAO 1, 2 Ru-Ping DAI 3, 4, 5

Affiliation: 1. School of Medicine, Shanxi Datong University, Datong 037009, Shanxi Province, China 2. Datong Ruici Medical Imaging Diagnostic Center, Datong 037005, Shanxi Province, China 3. Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China 4. National Center for Cardiovascular Diseases, Beijing 102308, China 5. Department of Radiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing 100037, China

Keywords: Immunoglobulin G4 Coronary arteritis Diagnostic criteria Mistletoe sign

DOI: 10.12173/j.issn.1004-5511.202103038

Reference: Miao LS, Dai RP. Progress in the diagnosis of immunoglobulin G4-related coronary arteritis[J]. Yixue Xinzhi Zazhi, 2021, 31(6): 466-471. DOI: 10.12173/j.issn.1004-5511.202103038.[Article in Chinese]

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Abstract

The histopathological features of IgG4-related coronary arteritis involve a large number of IgG4-positive plasma cell infiltrates in the tissues of the coronary adventitia, causing adventitia fibrosis and diffuse enlargement, forming a boudoir mass around the coronary artery with neoplastic thickening of the artery wall. CT angiography of the coronary artery shows the thickening of the coronary vessel wall and the mistletoe sign formed by the surrounding tumor-like mass which are the characteristic manifestations of this disease. This article expounds on IgG4-related coronary arteritis and explains its pathogenesis, imaging features and diagnostic criteria. 

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References

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