Objective To explore the variation in different corneal morphologies in Pentacam Scheimpflug tomography and the feasibility of assisting diagnosis of abnormal corneal posterior surface height. Methods In this retrospective study 120 myopia patients (240 eyes) who underwent preoperative examination of corneal refractive surgery in Jiangsu province hospital from April 2020 to September 2020 were selected. All patients had a comprehensive eye refractive power examination, and were examined by Pentacam three-dimensional anterior segment analysis system. The anterior surface curvature (ASK), posterior surface curvature (PSK), anterior surface astigmatism (AAstig), posterior surface astigmatism (PAstig), central corneal thickness (CCT), corneal diameter (W-W), deviation (Df) of corneal anterior surface difference map, deviation (Db) of corneal posterior surface difference map and progress of corneal average thickness were selected from Pentacam anterior segment analysis system. They were divided into four groups according to corneal diameter, and the differences between groups and within groups were compared. Spearman rank correlation analysis was used to explore the related influencing factors of BAD-Do (belin/ambrosio enhenced ectasia display-overall deviation of normality), and a multiple linear regression model was established to find the main influencing factors of BAD-Do. Results All patients included in the study were divided into four groups according to corneal diameter, including group A, B, C and D. There are 36 eyes in group A, 76 eyes in group B, 82 eyes in group C and 46 eyes in group D. There was no significant difference in refractive power between groups, that is, spherical power, cylindrical power and corneal thickness. Pentacam measurement showed that there were significant differences between PSK groups in patients with different corneal diameters. In the aspect of overall normal deviation BAD-Do, there were significant differences between group A, group C and D. There were also significant differences between group B, group C and D, but there is no significant difference between group A and group B. By analyzing the correlation between BAD-Do and Pentacam parameters in each group, it was found that BAD-Do had no statistical correlation with refractive power and corneal thickness (P> 0.05), but it had a low correlation with PSK (r=-0.27, P=0.001). In addition, there was a weak correlation between BAD-Do value and corneal diameter (r=-0.39, P=0.001). Conclusion Corneal diameter and posterior surface curvature are the main factors affecting BAD-Do. The smaller the corneal diameter, the more likely the patients will have BAD-Do abnormality. In the interpretation of Pentacam results, the influence of corneal diameter and corneal posterior surface curvature on the results should be considered.
HomeArticlesVol 31,2021 No.3Detail
Variation analysis and influencing factors in different corneal morphologies measured by the Pentacam system
Published on May. 18, 2021Total Views: 13611 timesTotal Downloads: 5326 timesDownloadMobile
- Abstract
- Full-text
- References
Abstract
Full-text
References
1.Motlagh MN, Moshirfar M, Murri MS, et al. Pentacam corneal tomography for screening of refractive surgery candidates: a review of the literature, part I[J]. Med Hypothesis Discov Innov Ophthalmol, 2019, 8(3): 177-203.
2.Hashemi H, Heydarian S, Ali Yekta A, et al. Agreement between pentacam and handheld au-to-refractor/keratometer for keratometry measurement[J]. J Optom, 2019, 12(4): 232-239. DOI: 10.1016/j.optom.2019.06.001.
3.Ruiseñor Vázquez PR, Galletti JD, Minguez N, et al. Pentacam scheimpflug tomography findings in topo-graphically normal patients and subclinical keratoconus cases[J]. Am J Ophthalmol, 2014, 158(1): 32-40.e2. DOI: 10.1016/j.ajo.2014.03.018.
4.Chan E, Chong EW, Lingham G, et al. Prevalence of keratoconus based on scheimpflug imaging: the raine study[J]. Ophthalmology, 2021, 128(4): 515-521. DOI: 10.1016/j.ophtha.2020.08.020.
5.Hashemi H, Beiranvand A, Yekta A, et al. Pentacam top indices for diagnosing subclinical and defnite keratoconus[J]. J Curr Ophthalmol, 2016, 28(1): 21-26. DOI: 10.1016/j.joco.2016.01.009.
6.Sorkin N, Ohri A, Jung H, et al. Factors affecting central corneal thickness measurement agreement between Scheimpflug imaging and ultrasound pachymetry in keratoconus[J]. Br J Ophthalmol, 2020, bjophthalmol- 2020-317111. DOI: 10.1136/bjophthalmol-2020-317111.
7.Yu AY, Shao H, Pan A, et al. Corneal biomechanical properties in myopic eyes evaluated via Scheimpflug imaging[J]. BMC Ophthalmol, 2020, 20(1): 279. DOI: 10. 1186/s12886-020-01530-w.
8.曹开伟, 刘李娜, 孙煜林,等. 不同角膜直径对Pentacam角膜地形图中BAD系统关于角膜扩张分析结果的影响[J]. 中华眼科杂志, 2020, 56(10): 761-767. DOI: 10.3760/cma.j.cn 112142-20200220-00093.[Cao KW, Liu LN, Sun YL, et al. The influence of different corneal diameters on Belin/Ambrosio enhanced ectasia display of Pen-tacam corneal topography[J]. Zhonghua Yan Ke Za Zhi, 2020, 56(10): 761-767.]
9.Ding L, Wang J, Niu L, et al. Pentacam scheimpflug tomography findings in chinese patients with different corneal diameters[J]. J Refract Surg, 2020, 36(10): 688-695. DOI: 10.3928/1081597X-20200730-02.
10.Piñero DP, Saenz González C, Alió JL. Intraobserver and interobserver repeatability of curvature and aber-rometric measurements of the posterior corneal surface in normal eyes using Scheimpflug photog-raphy[J]. J Cataract Refract Surg, 2009, 35(1): 113-120. DOI: 10.1016/j.jcrs.2008. 10.010.
11.Qin B, Tang M, Li Y, et al. Anterior segment dimensions in Asian and Caucasian eyes measured by optical coherence tomography[J]. Ophthalmic Surg Lasers Imaging, 2012, 43(2): 135-142. DOI: 10.3928/15428877-20120102-03.
12.王子杨, 杨文利, 李栋军, 等. 新型生物测量仪Pentacam AXL、IOLMaster 700与IOLMaster 500对白内障眼部生物学参数测量的比较[J]. 中华眼科杂志, 2019, 55(7): 515-521. DOI: 10.3760/cma.j.issn.04 12-4081.2019.07.007. [Wang ZY, Yang WL, Li DJ, et al. Comparison of biometry with the Pentacam AXL, IOLMaster 700 and IOLMaster 500 in cataract patients[J]. Zhonghua Yan Ke Za Zhi, 2019, 55(7): 515-521.]
13.Thulasidas M, Teotia P. Evaluation of corneal topography and tomography in fellow eyes of unilateral keratoconus patients for early detection of subclinical keratoconus[J]. Indian J Ophthalmol, 2020, 68(11): 2415-2420. DOI: 10. 4103/ijo.IJO_2129_19.
14.Hashemi H, Pakzad R, Heydarian S, et al. Global and regional prevalence of strabismus: a comprehensive systematic review and meta-analysis[J]. Strabismus, 2019, 27(2): 54-65. DOI: 10.1080/09273972.2019.1604773.
15.Sedaghat MR, Momeni-Moghaddam H, Ambrósio R Jr, et al. Diagnostic ability of corneal shape and biome-chanical parameters for detecting frank keratoconus[J]. Cornea, 2018, 37(8): 1025-1034. DOI: 10.1097/ICO.000000000 0001639.
16.Baradaran-Rafii A, Motevasseli T, Yazdizadeh F, et al. Comparison between two scheimpflug anterior segment analyzers[J]. J Ophthalmic Vis Res, 2017, 12(1): 23-29. DOI: 10.4103/jovr.jovr_104_16.
17.Zhang M, Zhang F, Li Y, et al. Early diagnosis of keratoconus in Chinese myopic eyes by combining corvis st with pentacam[J]. Curr Eye Res, 2020, 45(2): 118-123. DOI: 10.1080/02713683.2019.1658787.
Popular Papers
-
Sinicization and reliability test of the Family Caregiver Care Stress Management Scale
Oct. 31, 20255570
-
The research progress of the diagnosis and treatment of Raynaud phenomenon
Dec. 29, 20255509
-
A Meta-analysis of the application effect of artificial intelligence-assisted teaching in medical education
Nov. 01, 20255481
-
Association with PM2.5 exposure and metabolic syndrome: a cross-sectional study in rural areas in three provinces of China
Dec. 29, 20255463
-
An introduction to Risk of Bias in Network Meta-analysis (RoB NMA) tool
Dec. 29, 20255390
-
Expression of CD226 in preeclamptic placentas and its role in trophoblast function
Dec. 29, 20255374
-
Progress of oncolytic virus therapy in urological cancers
Dec. 29, 20255371
-
Analysis of the disease burden of neonatal jaundice in China from 1990 to 2021
Dec. 29, 20255330
-
Analysis of influencing factors and predictive model construction of anti-tuberculosis drug-induced liver injury
Dec. 29, 20255216
-
The relationship between physical activity levels, sleep quality, and blood glucose in patients with type 2 diabetes mellitus
Dec. 29, 20255202
-
Prevalence and influencing factors of intraoperative hypothermia in pediatric patients: a Meta-analysis
Dec. 29, 20255069
-
Association between dietary quality and sarcopenic obesity: based on the NHANES database
Dec. 29, 20255067
-
Research progress on the correlation between PICC insertion site and catheterized pericardial effusion in premature infants
Dec. 29, 20255005
-
Research progress on epigenetic regulation in cognitive impairment of offspring caused by stress during pregnancy
Dec. 29, 20254941
-
The application of bioinformatics on academic thesis of Chinese graduate student: a bibliometric analysis based on VOSviewer
Dec. 29, 20254806
Welcome to visit Zhongnan Medical Journal Press Series journal website!