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HomeArticlesVol 33,2023 No.3Detail

The research progress into long non-coding RNA in non-small cell lung cancer

Published on Jun. 25, 2023Total Views: 2719 timesTotal Downloads: 1060 timesDownloadMobile

Author: Juan WANG 1 Xu HAN 1 Ning ZHAO 1 Hong-Tao GUO 2 Xing LIAO 1 Miao JIANG 1 Hao GU 1

Affiliation: 1. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China 2. Department of Rheumatology and Immunology, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou 450000, China

Keywords: Non-small cell lung cancer Long non-coding RNA Diagnosis Treatment Prognosis

DOI: 10.12173/j.issn.1004-5511.202207025

Reference: Wang J, Han X, Zhao N, Guo HT, Liao X, Jiang M, Gu H. The research progress into long non-coding RNA in non-small cell lung cancer[J]. Yixue Xinzhi Zazhi, 2023, 33(3): 228-236. DOI: 10.12173/j.issn.1004-5511.202207025.[Article in Chinese]

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Abstract

Non-small cell lung cancer (NSCLC) with high morbidity and mortality, is one of the most important subtypes of lung cancer, which poses a serious threat the human health. There are still many challenges in the diagnosis and treatment of NSCLC and there is currently a need to explore effective treatment targets and biomarkers for diagnosis and prognosis. Long noncoding RNA (lncRNA) is a non-coding RNA with a length of more than 200 nucleotides and plays a key role in the progress, diagnosis and treatment of carci-nomas. Many studies have investigated the dysregulation of lncRNA in NSCLC, which could regulate the proliferation, growth and progress of tumor cells and provide a potential application for diagnosis, treatment and prognosis of NSCLC in clinical settings. Therefore, this paper aims to demonstrate the progress of research into lncRNA related to occurrence, progress, diagnosis, treatment and prognosis of NSCLC.

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